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. 2019 Apr 14;9(4):83. doi: 10.3390/brainsci9040083
AC astrocyte
ACfp astrocyte foot processes
BBB blood-brain barrier
BM basement membrane
CBF cerebral blood flow
CKC control: lean non-diabetic female heterozygous +/-C57B/6Jbackground
CL capillary lumen
CNS central nervous system
DBC db/db homozygous +/+ obese -insulin resistant -female diabetic model
DBE db/db models treated with empagliflozin
EC endothelial cell
FIB/SEM focused ion beam/scanning electron microscopy
LOAD late onset Alzheimer’s disease
NVU neurovascular unit
Pc pericyte
PYR pyramidal neuron
T2DM type 2 diabetes mellitus
TEM transmission electron microscopy
TJ/AJ tight junction/adherens junction
RBC red blood cell
SGLT2i sodium glucose transporter 2 inhibitor