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. 2019 Mar 29;8(4):292. doi: 10.3390/cells8040292

Figure 3.

Figure 3

Granulocyte HOCl intercellular redox signaling inhibits tumor cell proliferation. C6 (A) or PC12 (B) tumor cells treated with granulocytes in the presence or absence of inhibitors (Man—hydroxyl radical scavenger; Tau—HOCl scavenger; His—singlet oxygen scavenger; APO—NADPH oxidase inhibitor; ABH—peroxidase inhibitor). Mean values ± SD are given, (*) significance p < 0.01, compared to untreated tumor cells, (**) significance p < 0.01 compared to co-culture of granulocytes and tumor cells, and p > 0.01 compared to tumor cells alone.