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Colonies formed 21 days after re-plating MDA-MB-231 cells previously exposed to 70 nM of different treatments for 48 h. Photograph of plate containing colonies (A) and photomicrographs of crystal violet stained colonies, amplification 10×, scale bar = 100 μm. Arrows indicate cells reassuming the senescence morphology (B). Abbreviations: DXR, doxorubicin; PTX, paclitaxel. Ratio in parenthesis refers to PTX:DXR molar ratio.
