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Simulation of cumulative SNR. Total SNR of pyruvate was simulated as a function of the flip angle and the number of excitations. Repetition time TR was set to 100 ms; pyruvate T1 was 35 s. Every image in the dynamic series is acquired with 24 excitations. Optimal flip angle was estimated after the acquisition of five images (corresponding to 120 excitations at the red line).
