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. 2019 May 2;12(5):982–995. doi: 10.1016/j.stemcr.2019.04.002

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Optical Mapping of EHS

(A) A sample activation map of EHS paced at 500 ms cycle length. Black lines indicate isochrones at 10 ms intervals. Rectangular symbol indicates pacing site.

(B) Sample voltage trace is shown from the site indicated by the magenta point in (A).

(C–E) APD₃₀ and APD₈₀ as function of pacing cycle length (PCL) (C), CVs in the longitudinal and transverse directions (D), and anisotropy ratios at different pacing rates for d54–58 EHS (E) (n = 4 independent EHS for PCL = 400 ms, and n = 6 independent EHS for PCL >400 ms). ^∗p < 0.05 for difference compared with anisotropy ratio at PCL = 1000 ms. Error bars denote SD.

See also Table S1, Video S2, and Figure S5.