Table 5.
Histopathological evaluation for nephroprotective effects of CMHE.
| Treatment Groups | Tubular Degeneration | Tubulo-Interstitial Inflammation | Tubular Necrosis |
|---|---|---|---|
| Normal Control | 0 | 0 | 0 |
| Toxic Control (Gentamicin 100 mg/kg/day) |
2 | 4 | 4 |
| Gentamicin + CMHE 250 mg/kg/day | 1 | 4 | 0 |
| Gentamicin + CMHE 500 mg/kg/day | 0 | 2 | 0 |
Values presented are on the basis of histopathological observations. Grade 0 = no damage, grade 1 = mild cellular degradations, grade 2 = moderate cellular degenerations, and grade 4 = severe deformities.