Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Molecular targets of PEA. (a) PEA can directly activate G protein-coupled receptor α (PPARα) or a cannabinoid receptor G protein-coupled receptor (GPR55). (b) PEA through the inhibition of the expression of fatty acid amide hydrolase (FAAH), may increase the endogenous levels of AEA and 2-AG, which directly activate cannabinoid receptor 2 (CB2) (or cannabinoid receptor 1, CB1) and transient receptor potential vanilloid receptor 1 (TRPV1) channels.
