Table 1.
Population characteristics, echocardiographic variables, and cTnI concentration of the 166 cats enrolled in this study
| Healthy | Equivocal | Mild HCM | Moderate HCM | Severe HCM | ATE | P‐value | |
|---|---|---|---|---|---|---|---|
| Total number | 87 | 15 | 16 | 10 | 34 | 4 | |
| Age (years) | 2.75 (1.5–5.92) | 3.33 (1.58‐8.58) | 9.92 (1.56–12.92)a | 11.46 (3.31–12.58)a | 6.38 (4.46–12.56)a | 5.46 (2.15‐6.52) | P = .001b |
| Body weight (kg) | 4.5 (4.00‐5.4) | 6.4 (4.5‐7.5) | 4.67 (3.5‐5.8) | 4.75 (3.95‐5.33) | 5.0 (4.0‐5.75) | 4.25 (3.63‐4.88) | P = .057b |
| Sex male / female |
34/53 | 11/4a | 11/5a | 8/2a | 32/2 | 1/3c | P = .000001b |
| IVSd (mm) | 4.36 (4.12‐4.76) | 5.10 (4.88‐5.42) | 6.07 (6.02‐6.21) | 6.49 (5.38‐6.72) | 6.45 (4.97‐7.5 | 6.44 (5.95‐7.26) | P < .0001d |
| LVIDd (mm) | 15.87 (14.76‐17.33) | 15.9 (14.64‐17.65) | 14.38 (12.74‐15.76) | 13.07 (12.31‐5.6) | 14.69 (11.5‐17.52) | 12.49 (10.24‐14.72) | P < .0001d |
| LVFWd (mm) | 4.39 (4.0‐4.71) | 5.17 (4.9‐5.43) | 5.28 (4.92‐6.1) | 6.29 (5.46‐6.66) | 8.39 (7.22‐8.81) | 7.74 (7.07‐8.43) | P < .0001d |
| LVIDs | 9.53 (8.49‐10.71) | 10.2 (7.35‐11.7) | 7.44 (4.98‐9.01) | 7.27 (5.77‐9.88) | 7.55 (6.18‐9.72) | 8.99 (7.15‐9.12) | P < .0001d |
| LA/Ao | 1.29 (1.19‐1.37) | 1.28 (1.21‐1.34) | 1.3 (1.26‐1.37) | 1.47 (1.38‐1.54) | 1.9 (1.57‐2.28) | 2.59 (1.78‐2.65) | P < .0001d |
| cTnI | 0.013 (0.006‐0.025) | 0.022 (0.013‐0.037)a | 0.1 (0.028‐0.58)a , e | 0.174 (0.121‐0.356)a , e | 0.760 (0.407‐2.53)a , e , f | 6.413 (4.336‐11.266)a , e , f , g | P < .000001b |
Data are expressed as median (IQR).
P < .05, if compared to the healthy control group. Post hoc analysis according to Conover.32
Kruskal–Wallis test followed by a post hoc analysis according to Conover.32
P < .05, if compared to the severe HCM group. Post hoc analysis according to Conover.32
Spearman rank correlation evaluating the effect of echocardiographic parameters on the cTnI concentration excluding ATE.
P < .05, if compared to the equivocal group. Post hoc analysis according to Conover.32
P < .05, if compared to the mild HCM group. Post hoc analysis according to Conover.32
P < .05, if compared to the moderate HCM group. Post hoc analysis according to Conover.32
Abbreviations: ATE, arterial thromboembolism; cTnI, cardiac troponin I; HCM, hypertrophic cardiomyopathy; IVSd, interventricular septum in diastole; LVIDd, left ventricular internal diameter in diastole; LVFWd, left ventricular free wall in diastole; LVIDs, left ventricular internal diameter in systole; LA/Ao, left‐atrial‐to‐aorta ratio.