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Transmission electron microscopy (TEM) analysis for evaluating the effect of dehydrocostus lactone on the apoptosis induction in BON-1 cells. A – Untreated control group, B–D –cells treated with 5, 50 and 100 μM dose of the compound (cells were observed at 8000× magnification). Appearance of vacuoles at higher doses is a sign of an early apoptotic event. All images are representatives of three biological replicates
