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. 2019 May 16;12:63. doi: 10.1186/s12920-019-0508-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Correlation matrix plot: Pairwise comparison correlation matrix heatmap of some methods results. Half heatmap is represented with colors while the other half is represented with numbers (both halfs represent the same). For those variant callers having FILTER column (“toolname”_HQ), only those variants having “PASS” tag were selected. The methods were divided in three main strategies for better visualization: Machine learning based (blue), standard filtering based (red) and individual tools results (green)