Table 1.
Biological processes (Gene Ontology terms) associated with the 42 differentially expressed miRNAs
| Biological process | Count | % | P-value | Fold Enrichment | Bonferroni |
|---|---|---|---|---|---|
| transcription, DNA-templated | 581 | 13.30 | 4.86E-13 | 1.29 | 3.52E-09 |
| positive regulation of transcription, DNA-templated | 188 | 4.30 | 4.20E-12 | 1.58 | 3.04E-08 |
| regulation of transcription, DNA-templated | 448 | 10.25 | 2.78E-10 | 1.29 | 2.01E-06 |
| negative regulation of transcription from RNA polymerase II promoter | 238 | 5.45 | 4.90E-10 | 1.43 | 3.54E-06 |
| positive regulation of transcription from RNA polymerase II promoter | 304 | 6.96 | 4.36E-09 | 1.34 | 3.16E-05 |
| cellular response to hypoxia | 48 | 1.10 | 2.53E-08 | 2.17 | 1.83E-04 |
| negative regulation of transcription, DNA-templated | 168 | 3.84 | 5.34E-08 | 1.46 | 3.86E-04 |
| positive regulation of cell migration | 76 | 1.74 | 6.07E-08 | 1.79 | 4.39E-04 |
| transforming growth factor beta receptor signalling pathway | 45 | 1.03 | 1.66E-07 | 2.12 | 0.001199 |
| apoptotic process | 181 | 4.14 | 9.54E-07 | 1.38 | 0.00688 |
| peptidyl-serine phosphorylation | 54 | 1.24 | 1.21E-06 | 1.87 | 0.008702 |
| positive regulation of cell proliferation | 151 | 3.46 | 3.27E-06 | 1.40 | 0.02335 |
| protein autophosphorylation | 67 | 1.53 | 4.51E-06 | 1.69 | 0.03212 |
| G1/S transition of mitotic cell cycle | 45 | 1.03 | 5.50E-06 | 1.91 | 0.03899 |
Gene Ontology designations were generated via DAVID functional annotation. Only terms with a Bonferroni-adjusted p ≤ 0.05 are presented