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. 2019 May 17;11:47. doi: 10.1186/s13195-019-0496-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Risk of incident dementia in the presence of a risk factor per 5-year age group (except for individuals ≥ 90, in which no upper age limit was used). Hazard ratio from model 1 (HR1) determined with Cox regression analyses adjusted for age at study entry and sex; hazard ratio from model 2 (HR2) determined with competing risk analyses adjusted for age at study entry and sex; the HR on the y-axis is graphed on a log scale. CI, confidence interval; *HRs changed significantly (p < 0.0071) between age groups, determined with trend analysis including the interaction of age group with risk factor