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. 2019 May 16;21:9. doi: 10.1186/s12575-019-0097-x

Table 1.

Assessment of infarct volume, NSS, body temperature, mortality and BBB breakdown in injured hemisphere. a = p < 0.01

Groups BBB n = 10 Infarcted Volume n = 10 Temperature n = 20 Mortality n (%)
Mean and SEM Variability% Mean and SEM % Variability% Mean and SEM °C Variability%
Naïve (n = 20) 1 section 80 ± 15 58 0.5 ± 0.3 191 37.2 °C
± 0.1
59 0%
2 section 113 ± 20 55 0.6 ± 0.2 86
3 section 174 ± 33 60 0.4 ± 0.3 209
4 section 151 ± 22 46 0.6 ± 0.3 187
5 section 161 ± 33 65 0.4 ± 0.3 250
6 section 127 ± 15 37 0.6 ± 0.3 149
Total Hemisphere 134 ± 11 25 0.5 ± 0.1 77
Laser 25jx1 (n = 20) 1 section 76 ± 36 148 1.1 ± 0.4 126 37.3 °C
± 0.1
61 0%
2 section 83 ± 31 120 0.4 ± 0.3 215
3 section 315 ± 172 172 1.2 ± 0.4 97
4 section 362 ± 118 103 0.5 ± 0.4 252
5 section 310 ± 47 48 1.4 ± 0.4 74
6 section 212 ± 28 42 0.6 ± 0.3 163
Total Hemisphere 234 ± 67 90 0.9 ± 0.1 49
Laser 50jx1 (n = 20) 1 section 53 ± 43 257 0.5 ± 0.2 142 37.3 °C
± 0.1
55 0%
2 section 233 ± 90 122 0.9 ± 0.3 116
3 section 556 ± 180 102 0.7 ± 0.3 115
4 section 418 ± 88a 67 0.8 ± 0.2 84
5 section 281 ± 99 112 0.8 ± 0.3 97
6 section 326 ± 90a 88 0.5 ± 0.3 173
Total Hemisphere 321 ± 63a 63 0.7 ± 0.1 47
Laser 50jx2 (n = 20) 1 section 89 ± 48 170 0.9 ± 0.2 81 37.3 °C
± 0.1
54 0%
2 section 308 ± 67a 69 0.5 ± 0.3 203
3 section 1072 ± 295a 87 0.6 ± 0.4 199
4 section 1147 ± 260a 72 0.4 ± 0.3 223
5 section 1262 ± 207a 52 0.5 ± 0.3 170
6 section 853 ± 271a 100 1.1 ± 0.3 87
Total Hemisphere 725 ± 100a 44 0.7 ± 0.1 48
Laser 50jx5 (n = 20) 1 section 617 ± 144a 74 2.3 ± 0.4a 51 37.4 °C
± 0.1
53 0%
2 section 854 ± 145a 53 1.3 ± 0.3 71
3 section 1114 ± 249a 71 2.0 ± 0.4a 59
4 section 1585 ± 385a 77 2.8 ± 0.6a 63
5 section 2027 ± 460a 72 1.2 ± 0.3 90
6 section 1332 ± 340a 81 1.7 ± 0.5 89
Total Hemisphere 1255 ± 167a 42 1.9 ± 0.5a 33
Laser 50jx10 (n = 20) 1 section 1359 ± 367a 85 2.2 ± 0.4a 58 37.4 °C
± 0.1
84 0%
2 section 2011 ± 431a 68 2.4 ± 0.5 69
3 section 1977 ± 318a 51 3.3 ± 0.5a 46
4 section 2632 ± 234a 28 3.8 ± 0.6a 51
5 section 2644 ± 340a 41 1.6 ± 0.5 92
6 section 2600 ± 529a 64 1.3 ± 0.6 162
Total Hemisphere 2204 ± 280a 40 2.4 ± 0.3a 34
t-MCAO (n = 25) 1 section 371 ± 211 179 0.5 ± 0.8 555 38.2 °C
± 0.1a
121 5 (17%)
2 section 1053 ± 377a 113 0.1 ± 0.7 1618
3 section 1806 ± 507a 89 6.8 ± 3.0 141
4 section 2108 ± 262a 39 2.2 ± 1.3a 192
5 section 2649 ± 688a 89 −0.1 ± 0.8 4625
6 section 2338 ± 322a 44 2.2 ± 1 151
Total Hemisphere 1688 ± 231a 43 1.9 ± 0.8 123
p-MCAO (n = 24) 1 section 355 ± 147 131 2.6 ± 1.3 164 38.3 °C
± 0.1a
129 6 (20%)
2 section 988 ± 200a 64 9.3 ± 4.7 159
3 section 3176 ± 750a 75 19.6 ± 6.6a 106
4 section 5213 ± 484a 29 16.8 ± 4.6a 87
5 section 3910 ± 649a 52 7.1 ± 3.6 161
6 section 2942 ± 477a 51 4.0 ± 2.8 228
Total Hemisphere 2764 ± 256a 29 9.9 ± 2.9a 92