Figure 6.

Fungal isolate-specific modulation of airway leukocyte recruitment and increased lung inflammatory cytokine expression in adiponectin-deficient mice in response to A. fumigatus aspiration. Wild-type or adiponectin-deficient mice aspirated 5 × 10⁶ conidia from Af293 or Af5517 isolates; lungs were harvested 48 h post-challenge for analysis of BALF cells for the indicated cell types by flow cytometry (A-D) or lung homogenate cytokine mRNA by qRT-PCR (E). N = 6–10/group. Data are a summary of two independent experiments for each fungal isolate. *p < 0.05, **p < 0.01, ***p < 0.001.