Table 3.
Genotypes and allele frequencies between ischemic stroke cases and controls
| SNP | Allele/genotype | Ischemic stroke | Control | Chi2/STAT | OR (95% CI) | P |
|---|---|---|---|---|---|---|
| rs6265 | A | 682(47.4) | 709(44.8) | – | – | – |
| G | 758(52.6) | 873(55.2) | 1.96 | 1.11(0.96–1.28) | a0.162 | |
| AA | 153(21.2) | 172(21.7) | – | – | – | |
| AG | 376(52.2) | 365(46.1) | – | – | – | |
| GG | 191(26.5) | 254(32.1) | – | – | – | |
| Dominantb | – | – | 0.73 | 1.11(0.83–1.48) | 0.467 | |
| Model | ||||||
| AA+GA | ||||||
| GG | ||||||
| Recessiveb | – | – | –1.735 | 0.75(0.55–1.04) | 0.083 | |
| Model | ||||||
| AA | ||||||
| GA+GG | ||||||
| rs7124442 | C | 126(8.7) | 133(8.6) | – | – | – |
| T | 1326(91.3) | 1415(91.4) | 0.01 | 1.01(0.78–1.31) | 0.924 | |
| CC | 3(0.4) | 6(0.8) | – | – | – | |
| TC | 120(16.5) | 121(15.6) | – | – | – | |
| TT | 603(83.1) | 647(83.6) | – | – | – | |
| Dominant | – | – | –0.14 | 0.98(0.69–1.39) | 0.89 | |
| Model | ||||||
| CC+TC | ||||||
| TT | ||||||
| Recessive | – | – | –0.33 | 0.75(0.14–3.94) | 0.739 | |
| Model | ||||||
| CC | ||||||
| TC+TT |
SNP: Single-nucleotide polymorphism; STAT: logistic coefficient t statistic; CI: confidence interval; OR: odds ratio. aChi-square test; blogistic regression analyses adjusted on the basis of risk factors such as age, sex, hypertension, hyperlipidemia, diabetes, atrial fibrillation, smoking and drinking.