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(a) A schematic of the relationship between probe, mutant (MT) target DNA (tDNA), wild type (WT), downstream reporter DNA (drDNA), and upstream reporter DNA (urDNA) for HBV 1762/1764 double mutation, (b) that for KRAS point mutation, and (c) the legend defining probe, MT, WT, drDNA, urDNA and fluorescent reporter microsphere (FRM) that was evenly coated with urDNA and drDNA.
