Table 1.
Analyses of 4.1 family members in breast cancer.
| Gene | Dataset | Normal (Case) | Tumor (Case) | Fold change | P-value | t-Test |
|---|---|---|---|---|---|---|
| 4.1G | Curtis breast | Breast (144) | Invasive ductal breast carcinoma (1556) | −2.396 | 1.37E–62 | −26.734 |
| Breast (144) | Invasive lobular breast carcinoma (148) | −2.165 | 8.00E–52 | −18.777 | ||
| Breast (144) | Invasive ductal and invasive Lobular breast carcinoma (90) |
−2.273 | 7.05E–43 | −17.468 | ||
| Breast (144) | Tubular breast carcinoma (67) | −2.113 | 1.37E–33 | −15.415 | ||
| Breast (144) | Mucinous breast carcinoma (46) | −2.557 | 1.13E–27 | −16.042 | ||
| Breast (144) | Invasive breast carcinoma (21) | −2.49 | 7.86E–10 | −9.273 | ||
| Breast (144) | Ductal breast carcinoma in situ (10) | −2.327 | 4.03E–05 | −6.346 | ||
| TCGA-breast | Breast (61) | Mixed lobular and ductal breast carcinoma (7) | −2.374 | 8.51E–06 | −6.286 | |
| Breast (61) | Invasive ductal and lobular breast carcinoma (3) | −2.321 | 2.00E–03 | −5.734 | ||
| Breast (61) | Mucinous breast carcinoma (4) | −2.13 | 0.006 | −4.11 | ||
| Richardson breast 2 | Breast (7) | Ductal breast carcinoma (40) | −2.693 | 2.36E–05 | −4.859 | |
| Ma breast 4 | Breast (14) | Ductal breast carcinoma in situ epithelia (9) | −2.057 | 2.00E–03 | −3.583 | |
| Sorlie breast | Breast (4) | Lobular breast carcinoma (4) | −2.456 | 0.04 | −2.275 | |
| Radvanyi breast | Breast (9) | Ductal breast carcinoma in situ (3) | −2.177 | 4.10E–02 | −1.984 | |
| 4.1B | Turashvili breast | Ductal breast cell (10) Lobular breast cell (10) |
Invasive ductal breast carcinoma (5) | 5.558 | 4.00E–03 | 0.004 |
| 4.1N | Turashvili breast | Ductal breast cell (10) Lobular breast cell (10) |
Invasive ductal breast carcinoma (5) | −2.154 | 5.00E–03 | −2.836 |
| Sorlie breast | Breast (4) | Fibroadenoma (3) | −2.311 | 0.011 | −3.992 | |
| Sorlie breast (2) | Breast (4) | Fibroadenoma (3) | −2.104 | 2.40E–02 | −3.22 | |
| Radvanyi breast | Breast (9) | Invasive lobular breast carcinoma (6) | 2.254 | 0.016 | 2.393 | |
| 4.1R | Radvanyi breast | Breast (5) | Invasive lobular breast carcinoma (7) | 4.357 | 8.00E–03 | 2.948 |
| Breast (5) | Invasive mixed breast carcinoma (3) | 4.015 | 0.009 | 3.644 |