Fig. 2.

Left-to-right columns present comparative OCT-based and histological results for: non-tumorous (normal) breast tissue, benign fibroadenoma (green box), non-invasive (blue box) and invasive (orange box) ductal breast carcinomas. Magenta-color (solid line) rectangles in the CP OCT and OCE images indicate the areas covered by respective histologic sections. The black dashed-line rectangles in the OCE images indicate the tissue areas, over which histograms of normalized stiffness spectrum were calculated. Letters in the images show areas of normal breast terminal duct lobular units (TDLUs); fibrous stroma (FS); adipose tissue (A), atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and agglomerates of tumor cells (TC). Scale bars correspond to 0.5 mm in all panels. Unlike Fig. 1(e) the upper silicone layer is not shown in the OCE images.