Date	Event	Description
10 October 2018	New search has been performed	New literature search was run
10 October 2018	New citation required and conclusions have changed	We added 6 additional studies including 14,504 adults (AUSTRI 2016; Bernstein 2017; Mansfield 2017; Raphael 2017; Sher 2017; Slankard 2016), as well as 3 additional studies including 6591 children (MASCOT 2013; Ploszczuk 2014; VESTRI 2016). The 2 large ongoing studies identified at the last update (NCT01462344; NCT01475721) are now included as AUSTRI 2016 and VESTRI 2016 Roman Jaeschke stepped down as an author of the review, and Sam Waterson and Ben Sayer joined as review authors