Optical images of bubbles produced by histotripsy pulses inside agarose tissue phantoms of increasing Young’s modulus. Images demonstrate a decrease in bubble size with increasing frequency and increasing medium stiffness. Reprinted from Physics in Medicine and Biology, vol. 60, Vlaisavljevich et al, Effects of tissue stiffness, ultrasound frequency, and pressure on histotripsy-induced cavitation bubble behavior, p. 2271,
doi.org/10.1088/0031-9155/60/6/2271. Copyright (2015), © Institute of Physics and Engineering in Medicine. Reproduced by permission of IOP Publishing. All rights reserved.