Table 2.
Laboratory and Point-of-Care Hemostatic Values Before and After 3F-PCC Administration
| Parameter (units) | Before (Mean ± SD) | After (Mean ± SD) |
|---|---|---|
| Fibrinogen (mg/dl) | 245.7 ± 83.5 | 256.0 ± 61.8 |
| Platelet count (x 109/L) | 115.4 ± 62.3 | 150.5 ± 54.5 |
| PT (s) | 20.6 ± 23.3 | 12.0 ± 4.3 |
| INR | 1.8 ± 2.0 | 1.0 ± 0.4 |
| aPTT(s) | 57.8 ± 72.7 | 34.4 ± 12.8 |
| A10 FIBTEM®(mm) | 14.2 ± 6.8 | 17.1 ± 8.0 |
| A10 EXTEM®(mm) | 43.2 ± 11.7 | 51.9 ± 6.9 |
| aCT EXTEM®(s) | 84.1 ± 32.4 | 65.5 ± 13.9 |
a
CT EXTEM® is not sensitive to unfractionated heparin within blood up to 4U/ml.
Abbreviations: PT=Prothrombin time (seconds); aPTT=Activated partial thromboplastin time; A10=Amplitude of the tracing at 10 minutes of run time; CT=Clotting time; FIBTEM=ROTEM® fibrinogen assay; EXTEM=ROTEM® extrinsic clotting pathway assay, INR=International normalized ratio