Table 1:
Baseline Demographics of Study Population by BMI group
| BMI (kg/m2) | < 25 | 25–29.9 | 30–39.9 | > 40 | p |
|---|---|---|---|---|---|
| n (female) | 37 (24) | 23 (14) | 39 (29) | 17 (13) | 0.58 |
| Age (years) | 37.4±15.5 | 36.8±11.8 | 40.1±14.2 | 39.6±12.4 | 0.76 |
| Race | 0.002 | ||||
| Caucasian | 31 | 12 | 16 | 10 | |
| Black | 3 | 9 | 22 | 5 | |
| Other | 3 | 2 | 1 | 2 | |
| Age of Asthma Onset (years) | 15.9±16.2 | 12.8±11.6 | 13.9±13.2 | 18.8±14.0 | 0.54 |
| Waist Circumference (cm) | 84.7±14.4 | 91.4±15.3 | 99.8±13.9 | 109.5±24.0 | < 0.001 |
| FEV1 (% pred) | 88.2±13.2 | 91.2±15.0 | 88.5±17.1 | 86.9±12.1 | 0.82 |
| FVC (% pred) | 96.8±13.3 | 103.5±15.8 | 97.6±15.5 | 94.9±12.1 | 0.22 |
| FEV1/FVC (% pred) | 91.4±9.2 | 88.3±8.7 | 90.5±8.7 | 91.9±8.7 | 0.52 |
| Peak flow (% pred) | 85.9±15.3 | 90.4±18.9 | 89.5±16.8 | 77.7±18.1 | 0.08 |
| PC20 (mg/ml) | 4.23±5.37 | 3.50±5.46 | 4.26±4.79 | 3.84±6.08 | 0.44‡ |
| ASUI (range 0–1)↑ | 0.71±0.20 | 0.73±0.15 | 0.73±0.19 | 0.67±0.19 | 0.70 |
| ACT (range 5–25)↑ | 15.7±2.9 | 16.1±3.1 | 15.8±3.2 | 14.3±3.6 | 0.33 |
BMI, body mass index; FEV1, forced expiratory volume in one second; FVC, forced vital capacity; FEV1/FVC, ratio of FEV1 to FVC; PC20, the provocative concentration of methacholine that induced a 20% fall in FEV1; ASUI, asthma symptom utility index; ACT, asthma control test
Values shown are mean ± SD,
↑
higher score indicative of better health
‡
p value shown for Kruskal Wallis test