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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Biochim Biophys Acta Rev Cancer. 2019 Jan 29;1871(2):225–239. doi: 10.1016/j.bbcan.2019.01.004

Figure 2.

Figure 2.

Synthetic Data for two isozymes with altered KM and enzyme increased enzyme concentration and/or increased Vmax activity to demonstrate the possibility that an isozyme with lower substrate affinity can give rise to higher activity even at sub-saturating substrate concentrations, if it also has either higher specific activity or if it is expressed at higher concentrations.