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Two intratumor redox subpopulations in DB-1 melanoma xenografts (mean ± SD)
| Group | Redox indices | Sub-population 1 | Sub-population 2 | Sub-population Difference % | p |
|---|---|---|---|---|---|
| Control (N = 5) | Fp (μM) | 51 ± 9 | 82 ± 22 | 60 % | 0.008 |
| NADH (μM) | 142 ± 53 | 209 ± 47 | 47 % | 0.003 | |
| Fp redox ratio | 0.18 ± 0.05 | 0.27 ± 0.05 | 46 % | 0.0006 | |
| LND-treated (N = 5) | Fp (μM) | 30 ± 11 | 64 ± 21 | 111 % | 0.005 |
| NADH (μM) | 101 ± 15 | 187 ± 61 | 86 % | 0.021 | |
| Fp redox ratio | 0.20 ± 0.06 | 0.32 ± 0.08 | 66 % | 0.015 |
