Figure 1.

Spatiotemporal Distribution of Committed Hematopoietic Progenitors in the Human Embryo

The number and type of CFU-Cs at different Carnegie stages (CS) are shown for the AGM region (A), yolk sac (YS) (B), embryonic liver (EL) (C), and umbilical cord (UC) (D). For these experiments, embryonic tissue was staged, dissected, dissociated, and plated directly into methylcellulose and analyzed 10–14 days later. For AGM, n ≥ 4. For YS, n = 2 except CS14 where n = 1. For EL, n = 1 except where error bars are shown where n = 4 (CS13) and n = 2 (CS16). For UC, n = 1. Error bars show the standard error of the mean (SEM). ee, embryonic equivalent. See also Figure S1.