Table 2.
Level of Repopulation in Mice Engrafted by Cultured Human Embryonic HSCs
| Experiment No. (CS) | AGM Region | Time after Transplantation (Weeks) | % Human CD45+ Cells |
||
|---|---|---|---|---|---|
| Blood | Bone Marrow | Spleen | |||
| B (16) | Anterior | 17 | 10.0 | 49.7 | 7.7 |
| C (17) | Posterior | 20 | 2.2 | 16.8 | 20.8 |
| 20 | 1.3 | 3.3 | 7.5 | ||
| 20 | 6.4 | 32 | 10.5 | ||
| D (17) | Whole | 12 | 0.1 | 1.6 | 0.4 |
| E (13) | Part 2 | 19 | 0.3 | 41.1 | 8.3 |
| F (16) | Part 2 | 16 | 0.9 | 15.7 | 0.6 |
| Part 3 | 16 | 2.6 | 27.2 | 3.1 | |
| G (16) | Part 2 | 27 | 1.6 | 15.8 | 3.3 |
| Part 3 | 33 | 1.5 | 10.8 | 5.6 | |
| I (17) | Part 2 | 21 | 3.0 | 22.4 | 6.8 |
| Part 3 | 21 | 2.7 | 12.1 | 2.8 | |
| Part 4 | 21 | 2.8 | 10.8 | 2.9 | |
| Liver | 21 | 22.0 | 23.4 | 23.9 | |
The level of repopulation of engrafted mice only is shown and corresponds to the engrafted mice indicated in bold in Table 1. (For example, Part 1 never gave engraftment, hence is not seen in this table). Parts 1–4 are described in Figure S2 and experiments correspond to those in Tables 1 and 3. The NSG mouse engrafted with embryonic liver is included for completeness. CS, Carnegie stage.