Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
α-1-Antitrypsin and C3a directly interact.
(a) C3a content in commercial human plasma-derived and recombinant α-1-antitrypsin was assessed by CBA anaphylatoxin flex set. (b–c) Direct physical interaction of α-1-antitrypsin with C3a was identified using (b) surface plasmon resonance (SPR) and (ii) microscale thermophoresis (MST) methodology. Curve fit analyses indicated Kd values of 8.4 μM (b) and 7.5 μM (c).
