Fig. 1.
Concentration–time profiles of a FT, b 5-FU, c CDHP in plasma and tears at day 1. Mean(± SD) concentrations (ng/mL) at 1, 2, 4, 8 h after S-1 administration are shown. FT, tegafur; 5-FU, 5-fluorouracil; CDHP, 5-chloro-2,4-dihydroxypyridine
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