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. 2019 May 17;9:7539. doi: 10.1038/s41598-019-44048-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression of IQGAP1 in PDAC tissues. (A,B) Expression of IQGAP1 in PDAC and peritumor tissues in TMAs was detected by IHC. Percentage of high expression of IQGAP1 (SI > 4) was detected in 65.5% and 15.9% of in PDAC tissues and matched peritumor tissues, respectively. (C,D) Protein and mRNA expression of IQGAP1 was detected in PDAC and paired adjacent tissue samples from 4 different patients. (E) High expression of IQGAP1 (SI > 4) was correlated with poor prognosis in PDAC patients. *P < 0.05, **P < 0.01, and ***P < 0.001.