Table 1.
Baseline characteristics and results of the screening colonoscopies in the control group and the periodontitis group.
| Control group (n = 2288) | Periodontitis group (n = 216) | P value† | |
|---|---|---|---|
| Male sex | 1269 (55.5%) | 142 (65.7%) | 0.004 |
| Age, years | 45.8 ± 10.8 | 51.9 ± 11.2 | <0.001 |
| Body mass index, kg/m2 | 23.7 ± 3.3 | 24.5 ± 3.3 | 0.001 |
| Metabolic syndrome | 238 (10.4%) | 33 (15.3%) | 0.027 |
| Waist circumference, cm | 84.3 ± 9.4 | 86.3 ± 8.8 | 0.002 |
| Hypertension | 662 (28.9%) | 94 (43.5%) | <0.001 |
| High fasting glucose | 278 (12.2%) | 52 (24.1%) | <0.001 |
| Triglycerides, mg/dL | 114.0 ± 77.7 | 120.0 ± 85.5 | 0.284 |
| HDL, mg/dL | 58.4 ± 15.7 | 54.8 ± 16.5 | 0.001 |
| LDL, mg/dL | 131.3 ± 34.3 | 128.9 ± 32.9 | 0.337 |
| Total cholesterol, mg/dL | 202.4 ± 36.1 | 200.2 ± 37.7 | 0.381 |
| Smoking (ever)* | 1003/2284 (43.9%) | 131/216 (60.6%) | <0.001 |
| Alcohol consumption* | 1230/2284 (53.9%) | 112/216 (51.9%) | 0.573 |
| FH of CRC | 128 (5.6%) | 16 (7.4%) | 0.274 |
| Aspirin use | 65 (2.8%) | 15 (6.9%) | 0.001 |
| Fatty liver | 746 (32.6%) | 78 (36.1%) | 0.294 |
| Physical activity | 1337 (58.4%) | 123 (56.9%) | 0.671 |
| Diverticulosis | 55 (2.4%) | 10 (4.6%) | 0.068 |
| Results of screening colonoscopy | |||
| Colorectal neoplasms (all) | 502 (21.9%) | 76 (35.2%) | <0.001 |
| Proximal colorectal neoplasms | 281 (12.3) | 54 (25.0) | <0.001 |
| Advanced colorectal neoplasms | 34 (1.5%) | 9 (4.2%) | 0.004 |
| Proximal advanced colorectal neoplasms | 20 (0.9%) | 7 (3.2%) | 0.001 |
Variables shown are numbers (percentages) or expressed as the mean ± standard deviation. *Some data are missing. †Differences in categorical variables between groups were analyzed using Chi-square test or Fisher’s exact test. Continuous variables were compared by Student’s t-test. Abbreviations: HDL, High-density lipoprotein; LDL, Low-density lipoprotein; FH of CRC, Family history of colorectal cancer.