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. 2019 May 17;9:7536. doi: 10.1038/s41598-019-44012-w

Table 2.

Performance of top models for each number of microbiome markers.

Number of microbiome markers Model string AIC Training Validation AUC in testing
Sensitivity Specificity Accuracy AUC Sensitivity Specificity Accuracy AUC
10 class~age + sex + g778 + g362 + g319 + g769 + g147 + g725 + g348 + g837 + g732 + g179 208.8 0.845 0.865 0.859 0.923 0.727 0.834 0.804 0.860 0.893
9 class~age + sex + g778 + g362 + g319 + g147 + g725 + g348 + g837 + g732 + g179 207.1 0.844 0.856 0.853 0.920 0.750 0.838 0.813 0.873 0.892
8 class~age + sex + g778 + g362 + g319 + g147 + g725 + g837 + g732 + g179 206.4 0.844 0.859 0.855 0.921 0.748 0.836 0.811 0.865 0.887
7 class~age + sex + g778 + g362 + g319 + g147 + g725 + g837 + g732 205.9 0.814 0.856 0.844 0.914 0.759 0.861 0.832 0.886 0.885
6 class~age + sex + g778 + g362 + g319 + g147 + g837 + g732 205.3 0.808 0.863 0.848 0.916 0.746 0.833 0.808 0.870 0.887
5* class~age + sex + g778 + g362 + g319 + g147 + g732 205.1 0.797 0.871 0.850 0.908 0.729 0.850 0.816 0.879 0.875
4 class~age + sex + g362 + g319 + g147 + g732 206.3 0.783 0.855 0.835 0.904 0.746 0.836 0.811 0.872 0.875
3 class~age + sex + g362 + g147 + g732 211.9 0.804 0.830 0.823 0.901 0.757 0.829 0.809 0.877 0.850
2 class~age + sex + g362 + g732 221.6 0.790 0.823 0.814 0.888 0.761 0.790 0.781 0.864 0.820
1 class~age + sex + g319 257.5 0.624 0.835 0.775 0.795 0.597 0.822 0.759 0.776 0.767
0 class~age + sex 321.6 0.633 0.572 0.589 0.660 0.637 0.571 0.590 0.650 0.562

*The finally selected model showing the lowest AIC.

**The OTU symbols are as following: g778, Pseudomonas; g362, Streptococcus; g319, Staphylococcus; g769, Acinetobacter; g147, Bifidobacterium; g725, Klebsiella; g348, Enterococcus; g837, Akkermansia; g732, Trabulsiella; g179, Prevotella.