Table 3.
Subgroups | Death | Heart failure | Ischemic stroke/systemic embolism |
---|---|---|---|
HR (95% CI) | HR (95% CI) | HR (95% CI) | |
Male | |||
No AF | 1 (reference) | 1 (reference) | 1 (reference) |
Pre-existing AF | 1.17 (0.99–1.40) | 1.25 (0.85–1.84) | 1.25 (0.83–1.87) |
New-onset AF | 1.53 (1.27–1.85) | 1.49 (1.01–2.20) | 1.63 (1.09–2.43) |
Female | |||
No AF | 1 (reference) | 1 (reference) | 1 (reference) |
Pre-existing AF | 1.22 (0.99–1.49) | 1.90 (1.28–2.84) | 0.99 (0.61–1.61) |
New-onset AF | 1.50 (1.20–1.87) | 2.02 (1.34–3.02) | 1.69 (1.12–2.55) |
p values for interaction | 0.856 | 0.305 | 0.628 |
Age < 65 y/o | |||
No AF | 1 (reference) | 1 (reference) | 1 (reference) |
Pre-existing AF | 1.89 (1.29–2.77) | 2.26 (1.14–4.48) | 1.16 (0.46–2.88) |
New-onset AF | 1.35 (0.85–2.17) | 1.77 (0.90–3.49) | 1.61 (0.77–3.37) |
Age ≥ 65 y/o | |||
No AF | 1 (reference) | 1 (reference) | 1 (reference) |
Pre-existing AF | 1.14 (0.99–1.31) | 1.46 (1.08–1.98) | 1.15 (0.82–1.60) |
New-onset AF | 1.49 (1.28–1.74) | 1.58 (1.16–2.15) | 1.65 (1.20–2.26) |
p values for interaction | 0.005 | 0.772 | 0.987 |
AF atrial fibrillation, CI confidence interval, HR hazard ratio