Fig. 2.

Kaplan–Meier estimates of the incidence of major secondary outcomes in the pravastatin and placebo groups. a Mortality from all causes. b Death due to coronary heart disease (CHD) or nonfatal myocardial infarction (MI). c Stroke of any type. The graphs show a reduction in risk in the pravastatin group for all-cause mortality, cardiovascular events, and stroke. For every 1000 patients in the pravastatin group, the analysis showed that death from any cause was avoided in 30 patients, death due to CHD or nonfatal MI in 35 patients, and stroke in eight patients.

Reproduced by permission from Elsevier, NEJM, Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group 1998;Vol 339(19):1349–1357