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. 2019 May 17;9:7532. doi: 10.1038/s41598-019-43992-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Decreased expression of Dab2 and E-cadherin expression in pancreatic cancer. (a) Dab2 mRNA expression was determined in individual normal and pancreatic tumor samples by qRT-PCR analysis as described in Methods. Shown is the mean value ± SD relative to the mean expression in normal samples, which was set to 1.0. (b) Stage-specific mRNA expression for Dab2 is shown for normal and pancreatic cancer tumor samples depicted in a. Mean expression values for each group is depicted by the bar. *p < 0.05. (c,d) mRNA Dab2 expression (RNA Seq V2 RSEM) and disease-free and recurred/progressed status was retrieved from the TCGA pancreatic adenocarcinoma dataset using cBioPortal. Shown is the box/whisker plots obtained from all tumors stratified by Stage (c) or Grade (d). * signifies p < 0.05.