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. 2019 May 17;9:7507. doi: 10.1038/s41598-019-43556-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Expression of six identified HSPs predicts survival of breast cancer patients. (A) Kaplan-Meier survival curves of overall survival based on gene expression in cohort of TCGA BRCA patients. Hazard ratios (HR) with 95% confidence intervals and p-values (log-rank test, Mantel-Haenszel) were calculated. (B) Distribution of heat shock gene expression in TCGA BRCA dataset. The dotted lines indicate the median gene expression used as a cutoff. Normalized log2 mRNA data were obtained from XENA browser.