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. 2019 May 17;9:7507. doi: 10.1038/s41598-019-43556-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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GSEA results for high-risk and low-risk groups. (A) GSEA plots of three most significantly enriched datasets in high-risk (top panel) or low-risk (bottom panel) groups are shown. The tables enumerate the genes in the pathway which were the most significantly enriched in high-risk versus low-risk group (top panel) or low-risk versus high-risk group (bottom panel). NES (normalized enrichment score), p-val (nominal p-value), FDR q-val (false discovery rate). (B) Normalized enrichment scores for GSEA analysis of MSigDB hallmark gene sets enriched in high-risk (RED) or low-risk (VIOLET) groups. Gene sets with p ≤ 0,05 and FDR ≤ 0,25 were shown.