Table 4.
Sample | Parameter | Group |
|||
---|---|---|---|---|---|
Control -male | Control -female | Exposure -male | Exposure -female | ||
Serum | Hepatic function | ||||
STP(g/dL) | 49 ± 2 | 49 ± 4 | 55 ± 3 | 54 ± 3 | |
ALB(g/dL) | 23.2 ± 0.8 | 24.3 ± 1.2 | 25.6 ± 1.5** | 26.5 ± 0.7 | |
A/G | 0.9 ± 0.1 | 1.0 ± 0.1 | 0.9 ± 0.0 | 1.0 ± 0.1 | |
TBIL(mg/dL) | 1.2 ± 0.4 | 0.6 ± 0.7 | 0.8 ± 0.6 | 1.0 ± 0.3 | |
DBIL(mg/dL) | 0.4 ± 0.3 | 0.1 ± 0.6 | 0.4 ± 0.3 | 0.1 ± 0.1 | |
ALT(IU/L) | 64 ± 8 | 65 ± 7 | 42 ± 9** | 53 ± 1 | |
ALP(IU/L) | 282 ± 24 | 163 ± 5 | 225 ± 41 | 158 ± 7* | |
GGT(IU/L) | 0.4 ± 1.1 | 1.3 ± 1.5 | 0.8 ± 0.4 | 1.5 ± 0.7 | |
ASTm(IU/L) | 45 ± 8 | 29 ± 12 | 26 ± 14* | 42 ± 4 | |
AST(IU/L) | 165 ± 36. | 139 ± 27 | 144 ± 41 | 171 ± 18 | |
LDH(IU/L) | 1094 ± 276 | 497 ± 222 | 650 ± 228* | 786 ± 98 | |
Renal function | |||||
CREA (mg/dL) | 19 ± 5 | 32 ± 1 | 24 ± 2 | 29 ± 1* | |
UREA(mmol/dL) | 6.6 ± 0.3 | 5.4 ± 0.2 | 6.1 ± 0.5 | 7.4 ± 0.1** | |
GLU (mg/dL) | 17.4 ± 2.0 | 21.1 ± 8.8 | 14.8 ± 3.3 | 17.7 ± 1.3 | |
UA (μmol/dL) | 225 ± 22 | 211 ± 144 | 149 ± 22* | 1 01 ± 9 | |
RBP(mg/L) | 0.4 ± 1.9 | 1.7 ± 2.1 | 1.2 ± 2.0 | 3.0 ± 1.4 | |
CysC(mg/L) | 0.19 ± 0.01 | 0.18 ± 0.01 | 0.18 ± 0.01 | 0.16 ± 0.07* | |
Cardiovascular function | |||||
CK (IU/L) | 4150 ± 2058 | 2456 ± 1803 | 3184 ± 1528 | ||
CK-MB (IU/L) | 1030 ± 144 | 526 ± 164 | 968 ± 148 | ||
ACE (IU/L) | 288 ± 18.0 | 271.7 ± 11.0 | 294.2 ± 15.1 | ||
Thyroid function | |||||
TT3 (ng/dL) | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.8 ± 0.0 | 0.8 ± 0.0 | |
TT4 (ng/dL) | 37.8 ± 5.2 | 40.5 ± 12.6 | 37.2 ± 1.8 | 36.7 ± 0.0 | |
FT3 (ng/dL) | 3.1 ± 0.4 | 3.1 ± 0.6 | 3.2 ± 0.3 | 2.9 ± 0.0 | |
FT4 (ng/dL) | 11.2 ± 1.9 | 11.8 ± 1.0 | 12.4 ± 0.9 | 11.6 ± 0.0 | |
Oxidative stress | |||||
Serum | SOD(IU/L) | 277 ± 36.7 | 149.7 ± 31.5 | 148.2 ± 51.5** | 179.5 ± 31.8 |
Lung tissue |
MDA (nmol/mg) | 27.0 ± 2.8 | 24.8 ± 2.5 | 34.5 ± 4.3* | 31.8 ± 0.1* |
Values represent the mean ± SEM, n = 15. Control-male vs. Exposure-male, Control-female vs. Exposure-female, * P < 0.05. * *P < 0.01.