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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Transfusion. 2019 Mar 21;59(4):1233–1245. doi: 10.1111/trf.15254

Figure 4. Anemia increases gut macrophage activation and pro-inflammatory cytokine production within the intestinal mucosa.

Figure 4.

(A-B) Quantification of percent CD44+, IFNγ+, TNFα+ and IFNγ/TNFα double positive, CD4+ (A) or CD8+ (B) T cells isolated from the lamina propria of control or anemic pups. (C-D) Quantification of percent CD40+, IFNγ+, TNFα+ and IFNγ/TNFα double positive macrophages (C) or dendritic cells (DCs) (D) isolated from the lamina propria of control or anemic pups. (E) Quantification of percent CD69+, IFNγ+, TNFα+ and IFNγ/TNFα double positive natural killer (NK) cells isolated from the lamina propria of control or anemic pups. Data are presented as mean ± SEM, *P < .05.