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. 2019 May 17;13:42. doi: 10.1186/s13036-019-0171-6

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Diagram showing the main steps considered during testing of the new cephalometric protocol, in which (a) a raw model is aligned according to the natural head position (NHP) by a clinical expert to define (b) the gold standard model; next (c) a randomly generated rigid transformation or (d) mesh warping together with a random rigid transformation is applied to the gold standard model to produce several (e) target and (f) warped models, respectively; finally in (g) and (h) the craniofacial symmetry procedures are used to recover the ideal anatomical alignment (i)