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. 2019 Apr 26;116(20):9979–9988. doi: 10.1073/pnas.1814440116

Fig. 3.

Fig. 3.

Sporozoite infection induces robust γδ-T cell activation that promotes IFN-γ responses. (A) Absolute number of splenic IFN-γ–expressing γδ-T cells at days 3 or 5 after Spz (n = 6–10 mice per group) or iRBC infection (n = 4–6 mice per group) **P < 0.01; ns, not significant; by Mann–Whitney U test compared with naïve. (B) Absolute number of splenic of IFN-γ–expressing CD4+ T cells, CD8+ T cells, and NK cells from WT and TCRδ−/− mice at day 5 after Spz and day 3 after iRBC infections (n = 5 mice per group). Data are represented as mean ± SEM. *P < 0.05; **P < 0.01; ns, not significant; by Mann–Whitney U test.