Fig. 5.

Nematode and arthropod Wirins interact through surfaces with similar chemical properties. (A) Open-book view of the RIG-5 homodimeric interface, with interface residues depicted in stick representation. Residues at the conserved hydrophobic core are colored yellow. (B) Open-book view of the ZIG-8–RIG-5 heterodimer, with the hydrophobic core in yellow, the periphery in cyan, and side chain-to-side chain polar interactions labeled.