Figure 1. F2 MAM-treated rats display an increase (~20%) in the expression of ventral hippocampal (vHipp) cannabinoid receptor interacting protein 1 (CNRIP1).
Quantification of CNRIP1 and cannabinoid 1 receptor (CB1R) protein expression in the vHipp of F2 MAM- and saline-treated rats (A). There is a significant correlation between CNRIP1 and CB1R in the vHipp of control rats and not in F2 MAM- treated rats (B; Pearson correlation; R2= 0.5254). In normal rats, co-immunoprecipitation revealed an association between CB1R and CNRIP1 (n= 4 rats). Representative films demonstrating CNRIP1 (C) and CB1R (D) expression.