Table 3.
Months | Group-1 (finasteride) | Group-2 (metformin) | Group-3 (combination) | |
HOMA-IR | 0. | 2.6 ± 0.6 | 3.5 ± 3.5a | 2.3 ± 1.7 |
12. | 1.2 ± 0.7*b | 1.4 ± 1.3* | 1.6 ± 1.2*b | |
AUC-Glucose | 0. | 13098 ± 2895b | 15018 ± 5023 | 15939 ± 5195b |
12. | 12124 ± 1568* | 11961 ± 3542* | 13606 ± 3522*c | |
AUC-Insulin | 0. | 5356 ± 4101 | 7203 ± 5044a | 5087 ± 2145 |
12. | 1689 ± 1652*d | 4109 ± 3213* | 3039 ± 1928* |
*: p <0.05 compared with before treatment in the same group; a: p <0.05 when the group-2 compared to the other two groups; b: p <0.05 when the group-3 compared to the group-1; c: p <0.05 when the group-3 compared to the other two groups; d: p <0.05 when the group-1 compared to the other two groups. (HOMA-IR: Homeostasis model assessment of insulin resistance index, AUC: Area under curve).