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. 2017 Jan-Mar;13(1):84–89. doi: 10.4183/aeb.2017.84

Table 3.

Insulin resistance parameters at baseline and after 12 months of treatment, and comparisons within and between patient groups

  Months Group-1 (finasteride) Group-2 (metformin) Group-3 (combination)
HOMA-IR 0. 2.6 ± 0.6 3.5 ± 3.5a 2.3 ± 1.7
12. 1.2 ± 0.7*b 1.4 ± 1.3* 1.6 ± 1.2*b
AUC-Glucose 0. 13098 ± 2895b 15018 ± 5023 15939 ± 5195b
12. 12124 ± 1568* 11961 ± 3542* 13606 ± 3522*c
AUC-Insulin 0. 5356 ± 4101 7203 ± 5044a 5087 ± 2145
12. 1689 ± 1652*d 4109 ± 3213* 3039 ± 1928*

*: p <0.05 compared with before treatment in the same group; a: p <0.05 when the group-2 compared to the other two groups; b: p <0.05 when the group-3 compared to the group-1; c: p <0.05 when the group-3 compared to the other two groups; d: p <0.05 when the group-1 compared to the other two groups. (HOMA-IR: Homeostasis model assessment of insulin resistance index, AUC: Area under curve).