Table 3.
Effects of annual and biannual community-wide treatment relative to annual school-based deworming on prevalence of hookworm and Trichuris trichiura
| Number positive of total respondents | Community prevalence (95% CI) | Absolute percentage change from baseline (95% CI) | Unadjusted risk ratio (95% CI) | p value | Adjusted risk ratio*(95% CI) | p value | ||
|---|---|---|---|---|---|---|---|---|
| Hookworm | ||||||||
| 12-month assessment | ||||||||
| School-based deworming | 1284 of 7957 | 16·1% (12·1 to 20·1) | −2·4% (−10·9 to 6·1) | 1 (ref) | .. | 1 (ref) | .. | |
| Annual community-wide treatment | 984 of 8355 | 11·8% (9·0 to 14·6) | −6·1% (−13·6 to −1·3) | 0·73 (0·52 to 1·03) | .. | 0·77 (0·65 to 0·91) | .. | |
| Biannual community-wide treatment | 836 of 8177 | 10·2% (7·6 to 12·9) | −10·4% (−15·5 to −6·0) | 0·64 (0·45 to 0·92) | 0·04 | 0·65 (0·53 to 0·78) | <0·001 | |
| 24-month assessment | ||||||||
| School-based deworming | 972 of 7058 | 13·8% (10·5 to 17·0) | −4·8% (−13·0 to 3·5) | 1 (ref) | .. | 1 (ref) | .. | |
| Annual community-wide treatment | 597 of 7446 | 8·0% (6·0 to 10·1) | −9·9% (−16·8 to −3·0) | 0·59 (0·42 to 0·83) | .. | 0·64 (0·52 to 0·78) | .. | |
| Biannual community-wide treatment | 453 of 7281 | 6·2% (4·9 to 7·5) | −14·4% (−21·4 to −7·4) | 0·46 (0·33 to 0·63) | <0·001 | 0·48 (0·41 to 0·57) | <0·001 | |
| Trichuris trichiura | ||||||||
| 12-month assessment | ||||||||
| School-based deworming | 296 of 7957 | 3·7% (1·8 to 5·7) | −0·5% (−6·2 to 5·2) | 1 (ref) | .. | 1 (ref) | .. | |
| Annual community-wide treatment | 223 of 8355 | 2·7% (1·7 to 3·6) | −0·2% (−4·5 to 4·1) | 0·70 (0·37 to 1·32) | .. | 1·18 (0·80 to 1·74) | .. | |
| Biannual community-wide treatment | 287 of 8177 | 3·5% (1·9 to 5·2) | −0·2% (−5·6 to 5·2) | 0·90 (0·45 to 1·81) | 0·47 | 1·16 (0·82 to 1·65) | 0·63 | |
| 24-month assessment | ||||||||
| School-based deworming | 292 of 7058 | 4·1% (1·9 to 6·4) | −0·1% (−5·9 to 5·7) | 1 (ref) | .. | 1 (ref) | .. | |
| Annual community-wide treatment | 197 of 7446 | 2·6% (1·7 to 3·6) | −0·3% (−4·7 to 4·2) | 0·65 (0·34 to 1·24) | .. | 1·20 (0·86 to 1·68) | .. | |
| Biannual community-wide treatment | 237 of 7281 | 3·3% (1·8 to 4·7) | −0·4% (−5·8 to 4·9) | 0·80 (0·40 to 1·61) | 0·41 | 1·01 (0·77 to 1·34) | 0·43 | |
p values correspond to the treatment group categorical variable.
*
Adjusted for stratification factors (subcounty, baseline cluster prevalence, and cluster size), urban or rural status and baseline cluster mean socioeconomic status, access to sanitation, and access to improved water. Sampling was done at randomly selected households, selecting one household member to participate at random.