Table 3.
Results of univariate and multivariate analyses of liver metastasis-free survival.
| Factors | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| Age (years) (<66/≥66) | 1.008 | 0.484–2.112 | 0.983 | |||
| Sex (male/female) | 1.696 | 0.805–3.798 | 0.167 | |||
| Preoperative CEA (≥5/<5) | 1.277 | 0.526–2.732 | 0.526 | |||
| Histological grade (other∗/Tub1–2) | 2.573 | 0.613–7.309 | 0.170 | |||
| Lymphatic invasion (present/absent) | 2.085 | 0.959–5.012 | 0.064 | |||
| Vascular invasion (present/absent) | 1.587 | 0.657–4.714 | 0.324 | |||
| TNM stage (3-4/1-2) | 8.232 | 2.896–34.536 | <0.001 | 7.789 | 2.737–32.700 | <0.001 |
| Oct4 expression (high/low) | 2.866 | 1.319–6.888 | 0.007 | 2.613 | 1.201–6.284 | 0.015 |
∗Other: poorly differentiated, mucinous adenocarcinoma, or squamous cell carcinoma. Tub1: well-differentiated adenocarcinoma; Tub2: moderately differentiated adenocarcinoma.