Table 3.
SNP | XFS/XFG | Control | χ 2 | P | OR (95% CI) |
---|---|---|---|---|---|
TBC1D21 | |||||
rs16958445 | |||||
Allele | |||||
G | 432 | 583 | 3.025 | 0.082 | 1.369 (0.960–1.953) |
A | 70 | 69 | |||
| |||||
ATXN2 | |||||
rs7137828 | |||||
Allele | |||||
T | 429 | 531 | 3.272 | 0.070 | 0.7467 (0.544–1.025) |
C | 73 | 121 | |||
| |||||
APOE | |||||
rs429358 | |||||
Allele | |||||
T | 452 | 587 | |||
C | 50 | 65 | <0.001 | 0.996 | 0.999 (0.677–1.473) |
| |||||
rs7412 | |||||
Allele | |||||
C | 468 | 610 | |||
T | 34 | 42 | 0.051 | 0.822 | 1.055 (0.661–1.685) |
| |||||
CLU | |||||
rs2279590 | |||||
Allele | |||||
C | 351 | 455 | |||
T | 151 | 197 | 0.002 | 0.961 | 0.994 (0.771–1.280) |
| |||||
AFAP1 | |||||
rs11732100 | |||||
Allele | |||||
C | 402 | 524 | |||
T | 100 | 128 | 0.015 | 0.903 | 1.018 (0.760–1.364) |
| |||||
TXNRD2 | |||||
rs35934224 | |||||
Allele | |||||
C | 446 | 574 | |||
T | 56 | 78 | 0.180 | 0.671 | 0.924 (0.642–1.331) |
| |||||
CACNA1A | |||||
rs4926244 | |||||
Allele | |||||
T | 401 | 515 | |||
C | 101 | 137 | 0.138 | 0.710 | 0.947 (0.710–1.263) |
| |||||
ABCA1 | |||||
rs2472493 | |||||
Allele | |||||
A | 301 | 391 | |||
G | 201 | 261 | <0.001 | 0.998 | 1.000 (0.789–1.269) |
| |||||
LOXL1 | |||||
rs41435250 | |||||
Allele | |||||
G | 379 | 552 | |||
T | 123 | 100 | 15.280 | <0.001 | 1.791 (1.334–2.405) |
| |||||
rs893818 | |||||
Allele | |||||
G | 418 | 442 | |||
A | 84 | 210 | 35.780 | <0.001 | 0.423 (0.318–0.563) |
| |||||
GAS7 | |||||
rs9897123 | |||||
Allele | |||||
C | 249 | 341 | |||
T | 253 | 311 | 0.827 | 0.363 | 1.114 (0.883–1.406) |
| |||||
CNTNAP2 | |||||
rs2107856 | |||||
Allele | |||||
G | 299 | 390 | |||
T | 203 | 262 | 0.008 | 0.930 | 1.011 (0.797–1.281) |
| |||||
rs2141388 | |||||
Allele | |||||
C | 301 | 391 | |||
T | 201 | 261 | <0.001 | 0.998 | 1.000 (0.789–1.269) |
G allele of rs41435250 of LOXL1 was the risk allele for the disorder. In contrast, G allele of rs893818 of LOXL1 was the protective allele for the disorder. Other alleles of SNPs showed no statistical significance.