. 2019 May 2;2019:9687823. doi: 10.1155/2019/9687823

Table 4.

Genotype association analysis with these SNPs.

Gene/SNP	XFS/XFG	Control	p	OR (95% CI)	Adjusted-P	Adjusted-OR (95% CI)
TBC1D21
rs16958445
Genotype
GG	189	259	0.532	1.138 (0.758–1.71)	0.114	1.465 (0.913–2.351)
GA	54	65	0.033	5.481 (1.151–26.110)	0.043	5.439 (1.053–28.090)
AA	8	2	0.033	5.481 (1.151–26.110)	0.043	5.439 (1.053–28.090)

ATXN2
rs7137828
Genotype
TT	183	224	0.705	0.929 (0.635–1.360)	0.955	1.013 (0.654–1.569)
TC	63	83	0.027	0.322 (0.118–0.879)	0.030	0.299 (0.100–0.891)
CC	5	19	0.027	0.322 (0.118–0.879)	0.030	0.299 (0.100–0.891)

APOE
rs429358
Genotype
TT	202	263	0.910	1.025 (0.673–1.560)	0.532	1.171 (0.714–1.920)
TC	48	61	0.727	0.651 (0.059–7.230)	0.773	0.697 (0.060–8.091)
CC	1	2	0.727	0.651 (0.059–7.230)	0.773	0.697 (0.060–8.091)

rs7412
Genotype
CC	219	286	0.907	1.031 (0.619–1.717)	0.873	1.049 (0.585–1.882)
CT	30	38	0.790	1.306 (0.183–9.344)	0.887	1.172 (0.132–10.400)
TT	2	2	0.790	1.306 (0.183–9.344)	0.887	1.172 (0.132–10.400)

CLU
rs2279590
Genotype
CC	126	159	0.604	0.912 (0.644–1.292)	0.298	0.807 (0.538–1.209)
CT	99	137	0.760	1.094 (0.616–1.943)	0.171	1.586 (0.819–3.071)
TT	26	30	0.760	1.094 (0.616–1.943)	0.171	1.586 (0.819–3.071)

AFAP1
rs11732100
Genotype
CC	162	208	0.678	0.927 (0.649–1.324)	0.922	0.979 (0.650–1.477)
CT	78	108	0.442	1.412 (0.585–3.407)	0.576	0.711 (0.215–2.350)
TT	11	10	0.442	1.412 (0.585–3.407)	0.576	0.711 (0.215–2.350)

TXNRD2
rs35934224
Genotype
CC	203	252	0.118	0.709 (0.461–1.091)	0.175	0.710 (0.433–1.165)
CT	40	70	0.142	2.483 (0.737–8.362)	0.258	2.245 (0.553–9.114)
TT	8	4	0.142	2.483 (0.737–8.362)	0.258	2.245 (0.553–9.114)

CACNA1A
rs4926244
Genotype
TT	165	205	0.349	0.840 (0.584–1.209)	0.224	0.774 (0.512–1.170)
TC	71	105	0.684	1.165 (0.559–2.426)	0.826	0.901 (0.356–2.282)
CC	15	16	0.684	1.165 (0.559–2.426)	0.826	0.901 (0.356–2.282)

ABCA1
rs2472493
Genotype
AA	91	115	0.713	0.934 (0.650–1.343)	0.831	0.955 (0.626–1.457)
AG	119	161	0.888	1.036 (0.631–1.702)	0.906	0.966 (0.544–1.716)
GG	41	50	0.888	1.036 (0.631–1.702)	0.906	0.966 (0.544–1.716)

LOXL1
rs41435250
Genotype
GG	145	233	0.006	1.663 (1.158–2.388)	0.071	1.478 (0.966–2.259)
GT	89	86	0.003	3.902 (1.580–9.640)	0.003	5.276 (1.748–15.930)
TT	17	7	0.003	3.902 (1.580–9.640)	0.003	5.276 (1.748–15.930)

rs893818
Genotype
GG	171	154	<0.001	0.511 (0.358–0.729)	<0.001	0.4449 (0.293–0.676)
GA	76	134	<0.001	0.095 (0.033–0.272)	<0.001	0.119 (0.039–0.356)
AA	4	38	<0.001	0.095 (0.033–0.272)	<0.001	0.119 (0.039–0.356)

GAS7
rs9897123
Genotype
CC	62	82	0.739	0.934 (0.625–1.396)	0.440	0.833 (0.523–1.325)
CT	125	177	0.335	1.263 (0.785–2.033)	0.808	0.935 (0.542–1.612)
TT	64	67	0.335	1.263 (0.785–2.033)	0.808	0.935 (0.542–1.612)

CNTNAP2
rs2107856
Genotype
GG	89	117	0.917	1.02 (0.709–1.467)	0.687	1.091 (0.715–1.665)
GT	121	156	0.947	1.017 (0.622–1.664)	0.537	1.194 (0.681–2.094)
TT	41	53	0.947	1.017 (0.622–1.664)	0.537	1.194 (0.681–2.094)

rs2141388
Genotype
CC	91	118	0.981	0.996 (0.692–1.431)	0.772	1.064 (0.698–1.624)
CT	119	155	0.990	1.003 (0.614–1.639)	0.570	1.177 (0.672–2.060)
TT	41	53	0.990	1.003 (0.614–1.639)	0.570	1.177 (0.672–2.060)

The genotypes AA for rs16958445 of TBC1D21 and GG/TT for rs41435250 of LOXL1 were risk genotypes for the disease. The genotypes CC for rs7137828 of ATXN2 and GG/AA for rs893818 of LOXL1 were protective genotypes for the disease.