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. 2019 May 5;2019:9484717. doi: 10.1155/2019/9484717

Figure 4.

Figure 4

The relationship of CAC scores and metformin usage in smokers and never-smokers. Multivariable logistic regression revealed a significant association between metformin and CAC scores in male smokers before (OR [95% CI] = 0.40 [0.17–0.94]; P = 0.034) and after propensity score matching (PSM, OR [95% CI] = 0.38 [0.16–0.93]; P = 0.035) (a), but the association was not observed in never-smokers (OR [95% CI] = 0.72 [0.34–1.51]; P = 0.383) (b). BMI: body mass index; DM: diabetes mellitus; HTN: hypertension; eGFR: estimated glomerular filtration rate; NMA: nonmetformin antidiabetic agents.