Table 8.
Gastric mucosal changes at EGD according to the administration of LDASA and the rate of H. pylori detection.
| Altered gastric mucosa | H. pylori | Patients receiving LDASA, | Patients not receiving NSAID+LDASA, | Comparison group, | P; OR; (95%CI) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| n = 40 | n = 25 | n = 12 | |||||||||
| Antral gastritis, n (%) |
(+) | 27 (84.4) | 32 (80.0) | 14 (70.0) | 20 (80.0) | 3 (60.0) | 5 (41.7) |
P
1
= 0.016; OR = 5.6 (95% CI 1.40-22.36) |
P2 = 0.23; OR = 3.6 (95% CI 0.47-27.35) |
P3 = 0.63; OR = 1.0 (95% CI 0.29-3.49) |
P4 = 0.19; OR = 2.31 (95% CI 0.60- 8.94) |
| (-) | 5 (15.6) | 6 (30.0) | 2 (40.0) | ||||||||
|
| |||||||||||
| Pangastritis, n (%) |
(+) | 0 | 0 | 5 (100.0) | 5 (20.0) | 2 (100.0) | 2 (16.7) |
P
1
= 0.05; OR = 0 (95% CI 0-NaN) |
P2 = 1 |
P
3
= 0.006; OR = 0 (95% CI 0-NaN) |
P4 = 1 |
| (-) | 0 | 0 | 0 | ||||||||
|
| |||||||||||
| Gastric mucosal erosion, n (%) |
(+) | 10 (90.9) | 11 (27.5) | 3 (60.0) | 5 (20.0) | 2 (100.0) | 2 (16.7) | P1 = 0.36; OR = 1.90 (95% CI 0.36-10.07) |
P2 = 0.85; OR = 0 (95% CI 0 -NaN) |
P3 = 0.35; OR = 1.52 (95% CI 0.46-5.04) |
P4 = 0.21; OR = 6.67 (95% CI 0.44-101.74) |
| (-) | 1 (9.1) | 2 (40.0) | 0 | ||||||||
|
| |||||||||||
| Gastric mucosal hemorrhage, n (%) |
(+) | 3 (75.0) | 4 (10.0) | 2 (100) | 2 (8.0) | 1 (100.0) | 1 (8.3) | P1 = 0.68; OR = 1.22 (95% CI 0.12-12.11) |
P2 = 0.80; OR = 0 (95% CI 0-NaN) |
P3 = 0.58; OR = 1.28 (95% CI 0.22-7.55) |
P4 = 0.67; OR = 0 (95% CI 0-NaN) |
| (-) | 1 (25.0) | 0 | 0 | ||||||||
|
| |||||||||||
| Intact gastric mucosa, n (%) |
(+) | 4 (80.0) | 5 (12.5) | 1 (50.0) | 2 (8.0) | 2 (50.0) | 4 (33.3) | P1 = 0.11; OR = 3.5 (95% CI 0.76-16.05) |
P2 = 0.40; OR = 4 (95% CI 0.21-75.66) |
P3 = 0.45; OR = 0.61 (95% CI 0.11-3.41) |
P4 = 0.52; OR = 4 (95% CI 0.12-136.97) |
| (-) | 1 (20.0) | 1 (50.0) | 2 (50.0) | ||||||||
Notes: LDASA: low-dose acetylsalicylic acid.
The percentage of patients with appropriate GM changes in the LDASA, non-NSAID+LDASA, and comparison groups was calculated from the total number of patients in the corresponding group.
The percentage of H. pylori-positive patients was calculated from the number of those with appropriate GM changes in the LDASA, non- NSAID+LDASA, and comparison groups.
Р1: comparison of the number of patients with and without appropriate GM changes in the comparison and LDASA groups.
Р2: comparison of the number of H. pylori-positive and H. pylori-negative patients with an appropriate GM change in the comparison and LDASA groups.
Р3: comparison of the number of patients with and without appropriate GM changes in the LDASA and non-LDASA groups.
Р4: comparison of the number of H. pylori-positive and H. pylori-negative patients with an appropriate GM change in the LDASA and non-LDASA groups.